The Cannabidiol , also known as CBD is one of the two most important cannabinoid components of the cannabis plant, which is found in varying proportions depending on the strain. While in some it is minimal, in others it may be the most abundant, or it may be found in proportions more or less the same as THC.
The plant has some compounds that have a psychoactive effect (alteration of the perception and modification of the state of mind) and others do not. Among the first are delta-9-THC, CBN (cannabinol) and delta-8-THC, with different potencies and concentrations in the plant, being the most powerful and abundant delta-9-THC. These compounds are responsible for producing the effects sought by recreational users, ie "the trip".
On the contrary, although CBD is a compound that acts in the central nervous system and therefore is psychotropic, it does not have the psychoactive effects of THC. On the contrary, it antagonizes the psychotomimetic effects (psychotic similes) that it produces.
Currently, CBD is the cannabinoid which is recognized as having more beneficial effects for the treatment of some symptoms and diseases, and with greater therapeutic margin; that is, with mild side effects in a wide range of doses. In general, CBD is very well tolerated.
Therapeutic properties of the CBD
The most important therapeutic properties of CBD, demonstrated with different quality of evidence are:
- anti-nausea and antiemetic
- Reducer of appetite for heroin, cocaine and alcohol
These properties make CBD to be used in the treatment of multiple diseases, some of which are:
- neurodegenerative diseases (for example, Alzheimer's, Parkinson's and Multiple Sclerosis)
- chemical dependencies
- autism spectrum disorder
- Chronic inflammatory diseases such as chronic polyarthritis, Crohn's disease, inflammatory bowel disease,
- accompaniment of chemotherapy
- antitumor treatment
Beyond its therapeutic uses, in some jurisdictions, CBD is recommended as a food supplement.
Adverse effects of CBD
Among the adverse effects, generally mild to moderate, when CBD is used in therapeutic doses may be tired, drowsiness, dry mouth, headache, dizziness and decreased appetite. In general they improve with the reduction of the dose of CBD and disappear when the administration is suspended.